What Is a Brain Aneurysm?

A brain aneurysm (also called a cerebral or intracranial aneurysm) is a weakened, ballooning area in the wall of an artery in the brain. Aneurysms can range from a few millimeters to several centimeters in size and vary in shape from simple berry-like outpouchings to complex, irregularly shaped lesions. They are more common than most people realize—studies suggest that 3 to 5 percent of the general population may harbor an unruptured brain aneurysm.

While most aneurysms never cause symptoms, a ruptured aneurysm causes a subarachnoid hemorrhage—a type of hemorrhagic stroke that is a medical emergency with significant risk of death or disability. Even unruptured aneurysms can cause symptoms by compressing nearby brain structures or nerves, and certain aneurysms carry a meaningful risk of future rupture based on their size, shape, location, and growth pattern.

Symptoms

Most unruptured aneurysms produce no symptoms and are found incidentally during imaging for other reasons. When symptoms do occur, they may include:

  • Sudden, severe headache (“worst headache of my life”) — a hallmark of rupture
  • Pain above or behind the eye
  • Double vision or drooping eyelid (especially with posterior communicating artery aneurysms)
  • Nausea, vomiting, neck stiffness (signs of subarachnoid hemorrhage)
  • Loss of consciousness or seizures (in severe cases)

Diagnosis

The diagnostic workup for brain aneurysms typically includes:

  • CT Angiography (CTA): A fast, non-invasive test that provides detailed images of brain blood vessels. Often the first-line screening tool.
  • MRI / MR Angiography (MRA): Provides high-resolution vessel imaging without radiation. Useful for screening and follow-up surveillance.
  • Cerebral Catheter Angiography: The gold standard for aneurysm evaluation. A microcatheter is navigated through the blood vessels (typically via the wrist) to obtain the highest-resolution images of the aneurysm’s size, shape, and relationship to surrounding vessels. Dr. Choudhri performs the majority of his diagnostic angiograms through transradial (wrist) access for patient comfort and safety.
  • Advanced Imaging: Choudhri utilizes high-resolution Micro-DynaCT during surgery for intraoperative perforator vessel mapping, enhancing safety during microsurgical clipping.

microsurgical Techniques

Treatment Options

The decision to treat a brain aneurysm—and which approach to use—depends on many factors including the aneurysm’s size, shape, location, growth pattern, and the patient’s age and overall health. Dr. Choudhri is one of a select group of neurosurgeons with formal training and expertise in both microsurgical and endovascular techniques, allowing him to recommend the optimal approach without bias.

Microsurgical Clipping

Through a carefully planned craniotomy, a tiny titanium clip is placed across the neck of the aneurysm to permanently exclude it from the blood circulation. Clipping has the longest track record of any aneurysm treatment and remains the best option for many aneurysm types, particularly those with wide necks, complex geometry, or critical branch vessels arising from the aneurysm dome.

Dr. Choudhri uses advanced intraoperative technologies including Micro-DynaCT angiography for real-time verification of clip placement and perforator vessel patency, neuronavigation, and continuous neurophysiological monitoring to maximize surgical safety.

Cerebral Bypass Surgery

For complex giant or fusiform aneurysms that cannot be treated with standard clipping or endovascular techniques, cerebral bypass surgery creates an alternative blood flow pathway, allowing the aneurysm-bearing vessel to be safely occluded. Dr. Choudhri founded the Penn Center for Cerebral Revascularization and has specialized expertise in bypass procedures.

Endovascular Coiling

Platinum microcoils are delivered through a microcatheter navigated inside the blood vessels to fill the aneurysm sac, promoting thrombosis and sealing the aneurysm from the inside. This minimally invasive approach avoids open craniotomy and typically allows faster recovery.

Dr. Choudhri frequently performs coiling procedures through transradial (wrist) access, allowing patients to sit up and walk immediately after the procedure rather than lying flat for hours.

Flow Diversion

A fine-mesh stent is placed across the neck of the aneurysm within the parent artery, redirecting blood flow away from the aneurysm and promoting gradual healing. Flow diversion has revolutionized the treatment of large, giant, and wide-necked aneurysms that were previously difficult to treat.

Flow Diversion Devices Used in Dr. Choudhri’s Practice
Pipeline Embolization Device (Medtronic): The most widely used flow diverter worldwide. Dr. Choudhri is a certified proctor for Pipeline, training other physicians in its use.
Surpass Streamline / Surpass Elite (Stryker): A next-generation braided flow diverter with enhanced wall apposition. Dr. Choudhri serves as a consultant and proctor for the Surpass Elite system.
FRED-X Flow Diverter (Terumo Neuro): A dual-layer flow diverter with an integrated inner stent for enhanced flow modification.

Intrasaccular Therapy (WEB Device)

Intrasaccular and Coil Technologies

WEB Intrasaccular Device (Terumo Neuro): Dr. Choudhri is a certified proctor and has extensive experience with WEB for complex wide-necked aneurysms.

Hydrogel Coils (Terumo Neuro): Bioactive coils that expand after deployment to enhance packing density and reduce recurrence.

OptiBlock / OptiMAX Coils (Balt): Large-volume coils optimized for vessel occlusion and efficient aneurysm packing. Dr. Choudhri is a Balt consultant.

Stent-Assisted Coiling

For aneurysms with wide necks where coils alone would not remain stable, a small stent is placed across the aneurysm neck to serve as a scaffold, and coils are packed through the stent mesh into the aneurysm.

Stent Technologies

LVIS EVO (Terumo Neuro): A next-generation, low-profile braided stent designed for stent-assisted coiling of complex aneurysms. Dr. Choudhri has presented extensively on LVIS EVO.

Dr. Choudhri's Expertise in Brain Aneurysms

Dr. Choudhri brings a uniquely comprehensive approach to brain aneurysm care. He is one of very few neurosurgeons nationally who is dual-trained in both microsurgical and endovascular techniques and who serves as a consultant and proctor for multiple device companies, giving him firsthand experience with the full range of treatment technologies. He is a sub-investigator on the PODCAST trial—a national NIH-funded study determining when aneurysm surveillance is safe versus when treatment is needed.
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